MedAesthetics Academy

Scientific library

What each technology is, how to read a technical comparison and what each term means. Last reviewed: October 29, 2026.

Botulinum toxin type A

It temporarily blocks the release of acetylcholine at the junction between nerve and muscle. Formulations differ in molecule size, excipients and how they are stored. A key point when comparing: one brand's units are not equivalent to another's.

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Hyaluronic acid fillers

They differ in hyaluronic acid concentration, cross-linking technology and the presence of lidocaine. The choice depends on the injection plane and the area.

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Collagen biostimulators

Instead of adding volume with a gel, they stimulate the tissue to produce collagen. The main materials are calcium hydroxylapatite, poly-L-lactic acid and polycaprolactone. Unlike hyaluronic acid, they are not dissolved by hyaluronidase.

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Q-switched and picosecond lasers

Both fragment pigment with very short pulses: Q-switched lasers in nanoseconds and picosecond lasers in pulses about a thousand times shorter. The wavelength determines which pigment colors are treated.

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Scalp analysis

Analyzers with magnification and polarized light make it possible to measure density, thickness and scalp condition, and to compare progress at each follow-up. Some systems add artificial intelligence to classify scalp type.

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Genetics and hair loss

Pharmacogenetic tests analyze variants associated with response to treatments. They guide the choice; they do not replace clinical diagnosis or trichoscopy.

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How to read a comparison

  • A laboratory study describes the material; a clinical trial measures outcomes in patients.
  • An FDA 510(k) clearance is not an approval: it certifies equivalence with another device.
  • Data published by the manufacturer and data published in a scientific journal do not carry the same weight. On our product pages we always state which is which.

Glossary

Hyaluronic acid
A molecule present in the skin. In fillers it is cross-linked so that it remains longer in the tissue.
Cross-linking
Chemical bonding of hyaluronic acid chains. The most widely used agent is called BDDE.
Biostimulator
An injectable that stimulates the production of the body's own collagen, such as calcium hydroxylapatite, poly-L-lactic acid or polycaprolactone.
Calcium hydroxylapatite
A mineral in microsphere form that, within a gel, acts as a biostimulator.
Botulinum toxin type A
A protein that temporarily blocks the signal from the nerve to the muscle.
kDa (kilodalton)
A unit used to measure the size of a molecule.
Complexing proteins
Proteins that accompany the toxin in some formulations.
Non-inferiority
A study result showing that a product is not worse than another within a margin set in advance.
Q-switched
A laser with nanosecond pulses.
Picoseconds
Pulses about a thousand times shorter than nanosecond pulses.
510(k)
U.S. FDA clearance based on equivalence with a device that is already cleared. It is not the same as an approval.
CE marking
The European Union conformity mark for medical devices.
MFDS
South Korea's food and drug regulator.
Pharmacogenetics
The study of how genes influence the response to a treatment.
Sanitary registration
Authorization from the Ministry of Health of Costa Rica to market a product in the country.
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